DOAC Therapy, CV Surgery, and Managing Bleeding, Alice Chen, MD, PhD, Newer anticoagulant and antiplatelet agents present significant challenges to planning and performing CV surgery. An overview of these medications, reversal agents, and a practical approach to managing bleeding in the perioperative setting will be presented. Intended Audience - Physicians, Residents, Managers, Supervisors, Administration; Level - Intermediate
Hemostatic Efficacy of Fibrinogen Concentrate Compared to Cryoprecipitate, Anil Panigrahi. Fibrinogen plays a critical role in hemostasis and there is increased understanding of the risk from acquired hypofibrinogenemia that occurs during acute trauma and in surgical patients. As a result, several studies have supported early fibrinogen replacement to improve hemostasis. Standard fibrinogen replacement involves transfusion of cryoprecipitate, however, there continues to be concerns regarding the safety of allogeneic blood products. With its increasing availability, lyophilized fibrinogen concentrates may serve as a safer, efficacious alternative. In this presentation, the benefits of fibrinogen replacement will be reviewed and the safety and clinical efficacy of fibrinogen concentrates relative to cryoprecipitate will be discussed. Intended Audience - Physicians, Residents, Managers, Supervisors, Administration; Level - Intermediate